Dacheng Road is the important "one-horizontal" component in the backbone road network of Xidong New Area in Wuxi, which connects East Wuxi Railway Station and high-speed rail business district in the west, and Wanshan Lake Eco-tech City in the east. By analyzing the location and traffic function of the road, the necessity of rapid improvement of Dacheng Road is discussed. Based on the functional orientation and traffic demand analysis, the overall scheme of Dacheng Road Expressway is determined, including design standards, construction scale, and entrance and exit layout. Combined with the conditions of the road red line, the road network and land development along the route, and landscape requirements, the laying form of the expressway is determined. The key node schemes, such as expressway intersection node and subway crossing node, which hopes to provide the reference for the design of similar projects.