The safety of high slope protection project located along the urban roads is not only the basic guarantee, but also should be combined with economic, aesthetic and impact on the surrounding environment to do a good job in local design. Relying on Nanjing Airport Second Passage Project, the stability of high slope of the current roads is analyzed from both qualitative and quantitative aspects. The dangerous sliding surface of the slope is simulated. Further combined with many factors of project geology, landscape, cost and construction convenience, the high slope protection measures mainly of anchor rod - frame beam are proposed. And the stability coefficient of slope under the normal conditions, rainstorm conditions and earthquake conditions after reinforcement is checked. Finally, combined with the theoretical calculation results checked by the slope monitoring data, the superiority of anchor rod - frame beam structure in high slope protection of urban roads are proved.