With the steady progress of domestic urbanization, the concept of smart transportation has been gradually and widely concerned. In the construction of smart transportation, on-board sensors cannot play a key role in avoiding road congestion and optimizing driving routes due to the limitations of their carriers. The model of vehicle-road collaboration has attracted more and more attention from researchers. Smart light poles become the best sensing carrier in the construction of smart transportation due to their scalability. A series of sensing devices such as monitoring facilities, broadcasting, large screens, various sensors and detectors can be installed on the poles. Relying on 5G technology, the relevant traffic management departments can control the real-time traffic operation more timely. By establishing both of the traffic-flow prediction model and the regional traffic coordination optimization model, the operation of road traffic flow in the short and medium term is predicted in advance. Relying on the city perception network and directional broadcasting system woven by 5G+ smart light poles, it can make quantitative decisions on vehicle owners along the way and carry out efficient and effective management of urban road traffic. Based on the engineering example of Shanghai 5G + smart light pole, analysis and research are made on the system of regional traffic coordination and optimization control, which is developed on the basis of traffic flow prediction model.